3-Bromo-5-methoxypyridine → HCID 66701425, compound

HRID 876230Notes

Reaction equation

HRID 876230 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1.[CH2:10]([C:12]1[CH:17]=[CH:16][C:15](B(O)O)=[CH:14][CH:13]=1)[CH3:11]>>[CH2:10]([C:12]1[CH:17]=[CH:16][C:15]([C:2]2[CH:3]=[N:4][CH:5]=[C:6]([O:8][CH3:9])[CH:7]=2)=[CH:14][CH:13]=1)[CH3:11]

Participants

3

Reactant 2

HCID 8171633-Bromo-5-methoxypyridineHCID 2734352Boronic acid, (4-ethylphenyl)-

Product 1

HCID 66701425HCID 66701425, compound

Procedure

5.0 g (27 mmol) of 3-bromo-5-methoxypyridine and 4.8 g (32 mmol, 1.2 eq.) of 4-ethylphenylboronic acid were reacted according to General Method 1A. Yield: 3.0 g (53% of theory)

Sources & evidence

ORD record
ord-23d7e0dbea5845f0a400a64be847f035
Source dataset
uspto-grants-2015_03
Patent number
US08987248B2

Reaction notes

Loading…