HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarboxylic acid → 1-(Cyclopropylcarbonyl)-5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarboxylic acid | HCID 15655 | — |
| Reactant | 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide | HCID 66701553 | — |
| Product | 1-(Cyclopropylcarbonyl)-5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide | HCID 46931414 | — |
Reaction Steps
68 mg (0.20 mmol) of 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide (Example 17A) and 19 mg (0.22 mmol, 1.1 eq.) of cyclopropanecarboxylic acid were reacted according to General Method 1. Yield: 38 mg (50% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987248B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-36417574dbc549e7aa857743e12d13ab |
| Source note | uspto-grants-2015_03 |