HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pivalic acid → 1-(2,2-dimethylpropanoyl)-5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pivalic acid | HCID 6417 | — |
| Reactant | 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide | HCID 66701553 | — |
| Product | 1-(2,2-dimethylpropanoyl)-5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide | HCID 46931308 | — |
Reaction Steps
68 mg (0.20 mmol) of 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide (Example 17A) and 22 mg (0.22 mmol, 1.1 eq.) of pivalic acid were reacted according to General Method 1. Yield: 37 mg (34% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987248B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-5c634a2a35984d0d977c9af59ad9dcce |
| Source note | uspto-grants-2015_03 |