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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 876266Generated: October 30, 2026

Cyclopropaneacetic acid → 1-(Cyclopropylacetyl)-5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide

https://huagongshe.com/reaction/876266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropaneacetic acidHCID 138440—
Reactant5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamideHCID 66701553—
Product1-(Cyclopropylacetyl)-5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamideHCID 46931307—

Reaction Steps

68 mg (0.20 mmol) of 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide (Example 17A) and 22 mg (0.22 mmol, 1.1 eq.) of cyclopropylacetic acid were reacted according to General Method 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987248B2
Source datasetuspto-grants-2015_03
ORD IDord-fbfec7d8c3ef425791c0ff27c3291169
Source noteuspto-grants-2015_03