HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxypropanoyl chloride → 5-(4-ethylphenyl)-1-(3-methoxypropanoyl)-N-phenylpiperidine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxypropanoyl chloride | HCID 2759728 | — |
| Reactant | 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide | HCID 66701553 | — |
| Product | 5-(4-ethylphenyl)-1-(3-methoxypropanoyl)-N-phenylpiperidine-3-carboxamide | HCID 66760759 | — |
Reaction Steps
62 mg (0.18 mmol) of 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide (Example 17A) and 33 mg (0.27 mmol, 1.5 eq.) of methoxypropionyl chloride were reacted according to General Method 2. Yield: 65 mg (91% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987248B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-65a47e3107dd445ab8d4b987a9a12574 |
| Source note | uspto-grants-2015_03 |