tert-Butyl isocyanate → HCID 66761056, compound

HRID 876275Notes

Reaction equation

HRID 876275 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:14][NH:13][CH2:12][CH:11]([C:15]([NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[O:16])[CH2:10]2)=[CH:5][CH:4]=1)[CH3:2].[C:24]([N:28]=[C:29]=[O:30])([CH3:27])([CH3:26])[CH3:25]>>[C:24]([NH:28][C:29]([N:13]1[CH2:14][CH:9]([C:6]2[CH:5]=[CH:4][C:3]([CH2:1][CH3:2])=[CH:8][CH:7]=2)[CH2:10][CH:11]([C:15]([NH:17][C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[O:16])[CH2:12]1)=[O:30])([CH3:27])([CH3:26])[CH3:25]

Participants

3

Reactant 2

HCID 62412tert-Butyl isocyanateHCID 667015535-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide

Product 1

HCID 66761056HCID 66761056, compound

Procedure

62 mg (0.20 mmol) of 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide (Example 17A) and 20 mg (0.20 mmol, 1.0 eq.) of tert-butyl isocyanate were reacted according to General Method 4.

Sources & evidence

ORD record
ord-62f745724636420d9a0e7beaceaff11d
Source dataset
uspto-grants-2015_03
Patent number
US08987248B2

Reaction notes

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