HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Ethyl-N-methylcarbamoyl chloride → Nl-Ethyl-5-(4-ethylphenyl)-Nl-methyl-N3-phenylpiperidine-1,3-dicarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Ethyl-N-methylcarbamoyl chloride | HCID 11240471 | — |
| Reactant | 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide | HCID 66701553 | — |
| Product | Nl-Ethyl-5-(4-ethylphenyl)-Nl-methyl-N3-phenylpiperidine-1,3-dicarboxamide | HCID 66761405 | — |
Reaction Steps
250 mg (0.74 mmol) of 5-(4-ethylphenyl)-N-phenylpiperidine-3-carboxamide (Example 17A) and 117 mg (0.96 mmol, 1.3 eq.) of ethyl(methyl)carbamoyl chloride were reacted according to General Method 3. Yield: 215 mg (74% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987248B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-1f400a53913d448eba95bf1e89d39b24 |
| Source note | uspto-grants-2015_03 |