HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxyaniline → 1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)-N-(3-methoxyphenyl)piperidine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxyaniline | HCID 10824 | — |
| Reactant | 1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-carboxylic acid | HCID 46164685 | — |
| Product | 1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)-N-(3-methoxyphenyl)piperidine-3-carboxamide | HCID 42865372 | — |
Reaction Steps
66 mg (0.20 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-carboxylic acid (Example 7A) and 27 mg (0.22 mmol, 1.1 eq.) of 3-methoxyaniline were reacted according to General Method 1. Yield: 52 mg (60% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987248B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-684de2849a77414d8ccc32318bc76f8c |
| Source note | uspto-grants-2015_03 |