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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 876285Generated: October 25, 2026

Benzoic Acid → N-[1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]benzamide

https://huagongshe.com/reaction/876285

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
Reactant1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetateHCID 66701344—
ProductN-[1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]benzamideHCID 66701584—

Reaction Steps

170 mg (0.41 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 8A) and 50 mg (0.41 mmol, 1.0 eq.) of benzoic acid were reacted according to General Method 1. Yield: 58 mg (35% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987248B2
Source datasetuspto-grants-2015_03
ORD IDord-5b99f2e8834e47cbb41dfa02804a1458
Source noteuspto-grants-2015_03