HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylsulfonic acid → N-[1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]-1-phenylmethanesulphonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylsulfonic acid | HCID 7532 | — |
| Reactant | 1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate | HCID 66701344 | — |
| Product | N-[1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]-1-phenylmethanesulphonamide | HCID 46931630 | — |
Reaction Steps
55 mg (0.12 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 7A) and 21 mg (0.11 mmol, 0.9 eq.) of phenylmethanesulphonic acid were reacted according to General Method 6. Yield: 14 mg (24% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987248B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-3229bcb1d7d4441dae8dc3f88b35e51f |
| Source note | uspto-grants-2015_03 |