Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Hydrazinyl-4-iodopyridine → N-[(E)-[8-[tert-butyl(dimethyl)silyl]oxyquinolin-2-yl]methylideneamino]-4-iodopyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Hydrazinyl-4-iodopyridine | HCID 53402897 | — |
| 반응물 | 8-(Tert-butyldimethylsilyloxy)quinoline-2-carbaldehyde | HCID 58567082 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-[(E)-[8-[tert-butyl(dimethyl)silyl]oxyquinolin-2-yl]methylideneamino]-4-iodopyridin-2-amine | HCID 178455024 | — |
반응 단계
To 8-(tert-butyldimethylsilyloxy)quinoline-2-carbaldehyde (3.21 g, 11.2 mmol) in DCM (30 mL) was added (Z)-1-(4-iodopyridin-2(1H)-ylidene)hydrazine (3.15 g, 13.4 mmol). The reaction was stirred for 1 hour, affording a yellow precipitate, which was collected by filtration and used without further purification in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08987251B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-2e91fce295d84afa8ba7a006dd522911 |
| 출처 메모 | uspto-grants-2015_03 |