HRID876448

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21263232

tert-Butyl (3-hydroxy-2,2-dimethylpropyl)carbamate

C10H21NO3

结构：Oc1cccc2ccc(-c3nnc4ccc(-c5ccccc5)cn34)nc12

HCID136337809

未命名化合物

PRODUCTS

生成物

结构：CC(C)(CNC(=O)OC(C)(C)C)COc1cccc2ccc(-c3nnc4ccc(-c5ccccc5)cn34)nc12

HCID67230353

未命名化合物

PROCEDURE

实验过程

Prepared as described in Example 9, Step A, using tert-butyl 3-hydroxy-2,2-dimethylpropylcarbamate in place of tert-butyl-4-hydroxypiperidine-1-carboxylate and 2-(6-phenyl-[1,2,4]triazolo[4,3-a]pyridine-3-yl)quinolin-8-ol in place of 2-([1,2,4]triazolo[4,3-a]pyridine-3-yl)quinolin-8-ol.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0d0b48cbbcf242ff93a27e72f3918cf1
来源数据集: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08987251B2
来源说明: uspto-grants-2015_03

反应 SMILES

[OH:1][CH2:2][C:3]([CH3:14])([CH3:13])[CH2:4][NH:5][C:6](=[O:12])[O:7][C:8]([CH3:11])([CH3:10])[CH3:9].[C:15]1([C:21]2[CH:22]=[CH:23][C:24]3[N:25]([C:27]([C:30]4[CH:39]=[CH:38][C:37]5[C:32](=[C:33](O)[CH:34]=[CH:35][CH:36]=5)[N:31]=4)=[N:28][N:29]=3)[CH:26]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH3:13][C:3]([CH3:14])([CH2:2][O:1][C:33]1[CH:34]=[CH:35][CH:36]=[C:37]2[C:32]=1[N:31]=[C:30]([C:27]1[N:25]3[CH:26]=[C:21]([C:15]4[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:22]=[CH:23][C:24]3=[N:29][N:28]=1)[CH:39]=[CH:38]2)[CH2:4][NH:5][C:6](=[O:12])[O:7][C:8]([CH3:9])([CH3:11])[CH3:10]