HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58717298, compound → HCID 136337787, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58717298 | HCID 58717298 | — |
| Reactant | (2R)-2-[(2R)-4-(4-fluoro-o-tolyl)-3-oxomorpholin-2-yl]-2-hydroxyacetic acid | HCID 67222078 | — |
| Reactant | HCID 178507458 | HCID 178507458 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 136337787 | HCID 136337787 | — |
Reaction Steps
According to the Step 1-3 in synthetic method for EXAMPLE 1, a cyclic carbonate analogue (0.11 g) derived from compound 63-6 and 3-(4-aminophenyl)-1,2,4-oxadiazol-5(2H)-one with DMF were used instead of 1-2 and 6-amino-1-bis(tert-butoxycarbonyl)aminoisoquinoline to obtain compound 64-1 (43.2 mg) as a pale pink amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987242B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-4029ae0cfd5241c2868ddb8d9470ee52 |
| Source note | uspto-grants-2015_03 |