HRID876585

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID519896

4-Amino-3-chlorobenzonitrile

C7H5ClN2

结构：CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nccc2cc(N)ccc12

HCID58717298

未命名化合物

结构：CC(C)(C)c1ccc(N2CCO[C@H]([C@@H](O)C(=O)O)C2=O)cc1

HCID67032827

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1ccc(N2CCO[C@H]([C@@H](O)C(=O)Nc3ccc(C#N)cc3Cl)C2=O)cc1

HCID67223362

未命名化合物

PROCEDURE

实验过程

According to the Step 1-3 in synthetic method for EXAMPLE 1, a cyclic carbonate analogue (0.2 g) derived from compound 52-4 and 4-amino-3-chlorobenzonitrile (91.6 mg) were used instead of 1-2 and 6-amino-1-bis(tert-butoxy carbonyl)aminoisoquinoline, under high concentration condition (1M), to obtain compound 66-1 (93.1 mg) as a colorless amorphous solid.