HRID876592
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
CONDITIONS
反应条件
- 温度
- 0 °C
PROCEDURE
实验过程
To a solution of the compound 70-5 (30 mg) in MeOH (2 mL) at 0° C. was added 7M NH3/MeOH (0.3 mL) dropwise. The mixture was stirred for 1 h at 0° C. and an additional hour at rt. The mixture was concentrated under reduced pressure and placed under high vacuum to afford compound 70-6 (27 mg) as a clear glass. LC-MS: M+H=480 (free base).
WORKUP
后处理
- concentrationThe mixture was concentrated under reduced pressure