HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiopheneboronic acid → HCID 67222388, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiopheneboronic acid | HCID 2733960 | — |
| Reactant | 1-tert-Butoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazole | HCID 46705337 | — |
| Reactant | HCID 67223356 | HCID 67223356 | — |
| Product | HCID 67222388 | HCID 67222388 | 62.7% |
Reaction Steps
According to the Step 22-1 in synthetic method for EXAMPLE 22, compound 107-1 (0.2 g) and 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylic acid 1,1-dimethylethyl ester (0.27 g) were used instead of 14-4 and 2-thiopheneboronic acid to obtain compound 107-2 (137 mg) as a pale yellow amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987242B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-d920ecf4ce1e46049b9bdbb5dca40dcc |
| Source note | uspto-grants-2015_03 |