HCID 67223548, compound → HCID 67223546, compound

HRID 876612Notes

Reaction equation

HRID 876612 reaction equation
[CH2:1]([O:3][C:4](=[O:31])[CH:5]([CH:7]1[C:12](=[O:13])[N:11]([C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)[CH2:10][CH2:9][N:8]1C(OCC1C=CC=CC=1)=O)[OH:6])[CH3:2]>CCO>[OH:6][CH:5]([CH:7]1[C:12](=[O:13])[N:11]([C:14]2[CH:15]=[CH:16][C:17]([CH3:20])=[CH:18][CH:19]=2)[CH2:10][CH2:9][NH:8]1)[C:4]([O:3][CH2:1][CH3:2])=[O:31]

Participants

3

Reactant 1

HCID 67223548HCID 67223548, compound

Product 1

HCID 67223546HCID 67223546, compoundYield 97.3%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

According to the Step 33-1 in synthetic method for EXAMPLE 33, compound 109-1 (0.3 g) with EtOH was used instead of EXAMPLE 32 to obtain compound 109-2 (0.2 g) as a pale yellow amorphous solid.

Sources & evidence

ORD record
ord-2e5953ecd22f4e9ab95ccb1481199a46
Source dataset
uspto-grants-2015_03
Patent number
US08987242B2

Reaction notes

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