HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-[6-(Ethylsulfanyl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-[6-(Ethylsulfanyl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one | HCID 59603555 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-[6-(Ethylsulfanyl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one hydrochloride | HCID 67456990 | — |
Reaction Steps
35 mg (0.1 mmol) of the compound from Example 102 are stirred with 1.5 ml of a 4 N solution of hydrogen chloride in dioxane. The solid is filtered off, washed twice with tert-butyl methyl ether and dried under a high vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987261B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-746b9b7db46543d2aaa7cad183c33167 |
| Source note | uspto-grants-2015_03 |