HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 876765Generated: October 30, 2026
Ammonia methanol → Thieno[3,2-b]pyridin-2-ylmethanamine
https://huagongshe.com/reaction/876765
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia methanol | HCID 21705897 | — |
| Reactant | HCID 67305098 | HCID 67305098 | — |
| Product | Thieno[3,2-b]pyridin-2-ylmethanamine | HCID 67305714 | — |
Reaction Steps
2-(Chloromethyl)thieno[3,2-b]pyridine (C-5) (183 mg, 1 mmol) was dissolved in NH3/methanol (7 N, 10 mL). The resulting mixture was stirred at 50° C. for 16 hours and concentrated. The residue was purified by chromatography. MS (m/z): 165 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08987269B2 |
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| Source dataset | uspto-grants-2015_03 |
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| ORD ID | ord-7e8d186b05e7455f8033054b46d16bb3 |
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| Source note | uspto-grants-2015_03 |
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