[1,2,4]Triazolo[1,5-a]pyridine-6-carbonitrile → 1-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)methanamine

HRID 876788Notes

Reaction equation

HRID 876788 reaction equation
[N:1]1[CH:2]=[N:3][N:4]2[CH:9]=[C:8]([C:10]#[N:11])[CH:7]=[CH:6][C:5]=12.S1C2=NC=CC=C2C(CN)=C1>>[N:1]1[CH:2]=[N:3][N:4]2[CH:9]=[C:8]([CH2:10][NH2:11])[CH:7]=[CH:6][C:5]=12

Participants

3

Reactant 2

HCID 59214223[1,2,4]Triazolo[1,5-a]pyridine-6-carbonitrileHCID 67305656HCID 67305656, compound

Product 1

HCID 594626811-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)methanamine

Procedure

Intermediate L was prepared from [1,2,4]triazolo[1,5-a]pyridine-6-carbonitrile (L-2) following similar procedures for synthesizing intermediate J from J-4, as described above.

Sources & evidence

ORD record
ord-03f01201b9f94d288c805b53352aca1c
Source dataset
uspto-grants-2015_03
Patent number
US08987269B2

Reaction notes

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