4,6-dichloro-1-methyl-1H-pyrazolo(3,4-d)pyrimidine → HCID 58345952, compound

HRID 876939Notes

Reaction equation

HRID 876939 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=1.Cl[C:11]1[N:16]=[C:15]([Cl:17])[N:14]=[C:13]2[N:18]([CH3:21])[N:19]=[CH:20][C:12]=12>>[Cl:17][C:15]1[N:14]=[C:13]2[N:18]([CH3:21])[N:19]=[CH:20][C:12]2=[C:11]([NH:1][CH2:2][CH2:3][C:4]2[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=2)[N:16]=1

Participants

3

Reactant 2

HCID 2222474,6-dichloro-1-methyl-1H-pyrazolo(3,4-d)pyrimidineHCID 8540512-(Pyridin-3-yl)ethan-1-amine

Product 1

HCID 58345952HCID 58345952, compound

Procedure

Reaction of 3-(2-aminoethyl)pyridine with 4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 5 by General Procedure B gave (6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-(2-pyridin-3-yl-ethyl)-amine.

Sources & evidence

ORD record
ord-1d2829541a5e4e67a13bc0a41e12fb7d
Source dataset
uspto-grants-2015_03
Patent number
US08987280B2

Reaction notes

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