HCID 58345960, compound → HCID 44180386, compound

Participants

Reaction Steps

6-Chloro-4-(4-methane sulfonyl-piperazin-1-yl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine was reacted with indazole boronic acid pinacol ester using General Procedure A. Purification on silica yielded 149. NMR: (DMSO) 2.98 (3H, s), 3.35-3.40 (4H, m), 4.11 (3H, s), 4.18-4.22 (4H, m), 7.48-7.51 (1H, m), 7.70 (1H, d), 8.30 (1H, d), 8.42 (1H, s), 8.95 (1H, s). 13.20 (1H, s). MS: (ESI+) MH+=413

Provenance & Evidence