HCID 58345956, compound → HCID 44180610, compound

Participants

Reaction Steps

N-[4-(6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-phenyl]-acetamide was reacted with indazole boronic acid pinacol ester in General Procedure A. Purification on silica and trituration yielded 157. NMR: (CDCl3): 2.08 (s, 3H, CH3), 4.17 (s, 3H, CH3), 7.51 (t, H, ArH, J=7.77 Hz), 7.69 (m, 3H, 3×ArH), 7.78 (m, 2H, 2×ArH), 8.28 (d, H, ArH, J=7.26 Hz), 8.17 (sbr, H, NH), 8.93 (s, H, ArH), 9.98 (s, H, ArH), 10.07 (s, H, ArH), 13.18 (s, H, ArH). MS: (ESI+) MH+=399.13

Provenance & Evidence