4-Methylthiazole → HCID 44555149, compound

HRID 876982Notes

Reaction equation

HRID 876982 reaction equation
Cl[C:2]1[C:3]2[N:11]=[N:10][N:9]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]4([OH:25])[CH2:24][CH2:23][O:22][CH2:21][CH2:20]4)[N:14]=3)[C:4]=2[N:5]=[C:6]([NH2:8])[N:7]=1.[CH3:26][C:27]1[N:28]=[CH:29][S:30][CH:31]=1>>[CH3:26][C:27]1[N:28]=[C:29]([C:2]2[C:3]3[N:11]=[N:10][N:9]([CH2:12][C:13]4[CH:18]=[CH:17][CH:16]=[C:15]([C:19]5([OH:25])[CH2:24][CH2:23][O:22][CH2:21][CH2:20]5)[N:14]=4)[C:4]=3[N:5]=[C:6]([NH2:8])[N:7]=2)[S:30][CH:31]=1

Participants

3

Reactant 2

HCID 127484-MethylthiazoleHCID 86655325HCID 86655325, compound

Product 1

HCID 44555149HCID 44555149, compound

Procedure

This is prepared from 7-chloro-3-(6-[4-hydroxytetrahydropyran-4-yl]pyrid-2-ylmethyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine and 4-methylthiazole by the method of Example 38.

Sources & evidence

ORD record
ord-f302dd19a4ee435c8df97c90de6f7158
Source dataset
uspto-grants-2015_03
Patent number
US08987279B2

Reaction notes

Loading…