4-Methylthiazole → HCID 44555150, compound

HRID 876983Notes

Reaction equation

HRID 876983 reaction equation
Cl[C:2]1[C:3]2[N:11]=[N:10][N:9]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]4([OH:23])[CH2:22][CH2:21][CH2:20]4)[N:14]=3)[C:4]=2[N:5]=[C:6]([NH2:8])[N:7]=1.[CH3:24][C:25]1[N:26]=[CH:27][S:28][CH:29]=1>>[CH3:24][C:25]1[N:26]=[C:27]([C:2]2[C:3]3[N:11]=[N:10][N:9]([CH2:12][C:13]4[CH:18]=[CH:17][CH:16]=[C:15]([C:19]5([OH:23])[CH2:22][CH2:21][CH2:20]5)[N:14]=4)[C:4]=3[N:5]=[C:6]([NH2:8])[N:7]=2)[S:28][CH:29]=1

Participants

3

Reactant 2

HCID 127484-MethylthiazoleHCID 86655319HCID 86655319, compound

Product 1

HCID 44555150HCID 44555150, compound

Procedure

This is prepared from 7-chloro-3-(6-[1-hydroxycyclobutyl]pyrid-2-ylmethyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine and 4-methylthiazole by the method of Example 38.

Sources & evidence

ORD record
ord-26c95d1af604408499a64c76d897b8ea
Source dataset
uspto-grants-2015_03
Patent number
US08987279B2

Reaction notes

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