反应详情

At 130° C., 1.0 g (5.4 mmol) of 4,5-difluorophthalic anhydride was stirred in 6 ml of formamide for 2 h. After cooling, the reaction mixture was then added to ice-cold water. The precipitated yellow solid was filtered off with suction, washed thoroughly with cold water and dried under high vacuum. This gave 744 mg of a white solid (74.8% of theory).

1. temperatureAfter cooling
2. additionthe reaction mixture was then added to ice-cold water
3. filtrationThe precipitated yellow solid was filtered off with suction
4. washwashed thoroughly with cold water
5. customdried under high vacuum