反应详情

Under argon, 10.0 g (60.2 mmol) of 4-fluoro-2-benzofuran-1,3-dione were stirred at 130° C. in 50 ml of formamide for 1 h. The cooled reaction mixture was then added to ice-water. A solid precipitated out. This solid was filtered off with suction and washed with water. The product was dried under high vacuum. This gave 8.3 g (83% of theory) of the target compound.

1. customThe cooled reaction mixture
2. customA solid precipitated out
3. filtrationThis solid was filtered off with suction
4. washwashed with water
5. customThe product was dried under high vacuum