Bromine → HCID 87464204, compound

Participants

Reaction Steps

A mixture of 19.5 ml (380 mmol) of bromine and 300 ml of dichloromethane is added dropwise with exclusion of light to a solution, cooled to 0° C., of 86.2 g (350 mmol) of 2-(1-formylphenyl)-1-naphthylmethane in 1500 ml of dichloromethane. After stirring for a further 3 h, 1000 ml of 5% sodium sulfite solution are added, the mixture is stirred briefly, the organic phase is separated off, washed three times with 500 ml of water and evaporated in vacuo, and the residue is taken up in a little acetone. After standing for 24 h, the crystals are filtered off with suction, washed with acetone:n-hexane (1:1) and dried in vacuo. Yield: 90.7 g (279 mmol), 79.7%, purity about 98% (NMR).

Provenance & Evidence