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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 877319Generated: October 30, 2026

(4-(2,2-Dimethoxyethyl)phenyl)methanol → 4-(2,2-dimethoxyethyl)benzyl 3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate

https://huagongshe.com/reaction/877319

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-(2,2-Dimethoxyethyl)phenyl)methanolHCID 84773974—
Reactant3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino) methyl)phenoxy)methyl)benzoic acidHCID 86720819—
Reactantmethyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate hydrochlorideHCID 86720820—
Product4-(2,2-dimethoxyethyl)benzyl 3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoateHCID 86720818—

Reaction Steps

The title compound was prepared as described in Example 1 Step 10 with (4-(2,2-dimethoxyethyl)phenyl)methanol and 3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoic acid replacing 4-(2-hydroxyethoxy)-3-methylbenzaldehyde and methyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate hydrochloride respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987299B2
Source datasetuspto-grants-2015_03
ORD IDord-8f8ebda8737b4ce1bb17f8712d007284
Source noteuspto-grants-2015_03