HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-(2,2-Dimethoxyethyl)phenyl)methanol → 4-(2,2-dimethoxyethyl)benzyl 3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-(2,2-Dimethoxyethyl)phenyl)methanol | HCID 84773974 | — |
| Reactant | 3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino) methyl)phenoxy)methyl)benzoic acid | HCID 86720819 | — |
| Reactant | methyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate hydrochloride | HCID 86720820 | — |
| Product | 4-(2,2-dimethoxyethyl)benzyl 3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate | HCID 86720818 | — |
Reaction Steps
The title compound was prepared as described in Example 1 Step 10 with (4-(2,2-dimethoxyethyl)phenyl)methanol and 3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoic acid replacing 4-(2-hydroxyethoxy)-3-methylbenzaldehyde and methyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate hydrochloride respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987299B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-8f8ebda8737b4ce1bb17f8712d007284 |
| Source note | uspto-grants-2015_03 |