HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dioxolane-2-propanol → 3-(1,3-Dioxolan-2-yl)propyl 1-methyl-5((3((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)-1H-pyrazole-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dioxolane-2-propanol | HCID 11970929 | — |
| Reactant | 4-(2-Hydroxyethoxy)-3-methylbenzaldehyde | HCID 79111033 | — |
| Reactant | 1-methyl-5((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)-methyl)-1H-pyrazole-3-carboxylic acid | HCID 86720830 | — |
| Product | 3-(1,3-Dioxolan-2-yl)propyl 1-methyl-5((3((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)-1H-pyrazole-3-carboxylate | HCID 86720829 | — |
Reaction Steps
The title compound was prepared as described in Example 1 Step 10 with 1-methyl-5((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)-methyl)-1H-pyrazole-3-carboxylic acid and 3(1,3-dioxolan-2-yl)propan-1-ol replacing 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)-benzoic acid and 4-(2-hydroxyethoxy)-3-methylbenzaldehyde respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987299B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-05b0f5f7106141b785f914b326c3dd02 |
| Source note | uspto-grants-2015_03 |