HCID 24951004, compound → HCID 24951005, compound

Participants

Reaction Steps

The title compound was prepared from 9f (4.0 mg, 0.01 mmol) following general procedure A. Tritration with hexanes and Et2O afforded the title compound (1.0 mg, 25%) as a white solid: 1H NMR (acetone-d6, 600 MHz) δ 8.45 (dd, 1H, J=1.2, 7.7 Hz), 8.37 (dd, 1H, J=1.2, 7.8 Hz), 8.33 (t, 1H, J=7.7 Hz), 7.26 (t, 2H, J=7.5 Hz), 7.21 (d, 2H, J=6.9 Hz), 7.15 (t, 1H, J=7.3 Hz), 3.29 (t, 2H, J=7.2 Hz), 2.63 (t, 2H, J=7.7 Hz), 1.80 (m, 2H), 1.66 (m, 2H), 1.50 (m, 2H), 1.43 (m, 2H); 13C NMR (acetone-d6, 150 MHz) δ 188.9, 172.7, 169.9, 166.3, 150.5, 147.3, 144.5, 141.5, 130.2, 130.1, 128.7, 128.4, 127.4, 42.0, 37.4, 33.2, 31.3, 30.4, 24.6; HRMS-ESI-TOF m/z 380.1608 ([M+H]+, C21H21N3O4 requires 380.1605).

Provenance & Evidence