HCID 24949228, compound → HCID 24949377, compound

Participants

Reaction Steps

The title compound was prepared from 28 (8.7 mg, 0.021 mmol) following general procedure A. Preparative thin layer chromatography (SiO2, 0-4% AcOH-EtOAc) afforded the title compound (8.4 mg, 100%) as a white solid: 1H NMR (DMSO-d6+0.1% TFA, 600 MHz) δ 8.32 (d, 1H, J=7.7 Hz), 8.17 (d, 1H, J=7.8 Hz), 8.01 (t, 1H, J=7.9 Hz), 7.85 (br s, 1H), 7.48 (d, 2H, J=7.4 Hz), 7.45 (d, 2H, J=8.1 Hz), 7.28 (t, 2H, J=7.7 Hz), 7.25 (d, 2H, J=8.1 Hz), 7.18 (t, 1H, J=7.3 Hz), 3.45 (t, 2H, J=7.4 Hz), 3.01 (t, 2H, J=7.4 Hz); 13C NMR (DMSO-d6+0.1% TFA, 150 MHz) δ 188.0, 167.0, 166.1, 165.0, 163.0, 151.1, 144.2, 142.1, 141.2, 140.5, 140.4, 130.6, 130.4, 129.2, 128.8, 128.5, 128.2, 44.7, 29.9; HRMS-ESI-TOF m/z 400.1288 ([M+H]+, C23H17N3O4 requires 400.1292).

Provenance & Evidence