HCID 44577826, compound → HCID 44577867, compound

Participants

Reaction Steps

The title compound was prepared from 36 (7.5 mg, 0.017 mmol) following general procedure A. Flash chromatography (SiO2, 5% MeOH—CH2Cl2) afforded the title compound (6.5 mg, 95%) as a white solid: 1H NMR (DMSO-d6, 600 MHz) δ 8.26 (dd, 1H, J=8.4 Hz), 8.16 (dd, 1H, J=8.4 Hz), 8.06 (t, 1H, J=7.8 Hz), 7.55-7.51 (m, 4H), 7.36-7.33 (m, 3H), 7.24 (t, 1H, J=7.2 Hz), 4.26-4.22 (m, 1H), 3.13-2.99 (m, 2H), 2.86-2.84 (m, 2H); 13C NMR (DMSO-d6, 150 MHz) δ 167.2, 166.2, 164.2, 149.9, 144.1, 141.1, 139.6, 139.2, 138.7, 130.9, 129.5, 127.9, 127.5, 127.3, 126.3, 70.2, 43.4, 33.7; HRMS-ESI-TOF m/z 402.1443 ([M+H]+, C23H19N3O4 requires 402.1448).

Provenance & Evidence