N-bromobutanimide → HCID 117856921, compound

HRID 877445Notes

Reaction equation

HRID 877445 reaction equation
[Br:1]N1C(=O)CCC1=O.[CH3:9][S:10]([C:13]1[CH:14]=[C:15]([C:19]2[CH:24]=[CH:23][C:22]([C:25]3[N:29]([CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32])[N:28]=[C:27]([C:36]([F:39])([F:38])[F:37])[CH:26]=3)=[CH:21][CH:20]=2)[CH:16]=[CH:17][CH:18]=1)(=[O:12])=[O:11]>>[Br:1][C:26]1[C:27]([C:36]([F:39])([F:38])[F:37])=[N:28][N:29]([CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32])[C:25]=1[C:22]1[CH:23]=[CH:24][C:19]([C:15]2[CH:16]=[CH:17][CH:18]=[C:13]([S:10]([CH3:9])(=[O:11])=[O:12])[CH:14]=2)=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 89792952Ethyl 2-[5-[3′-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetate

Product 1

HCID 117856921HCID 117856921, compound

Procedure

Following bromination with N-bromosuccinimide, the title compound 37 is prepared starting from ethyl 2-(5-(3′-(methylsulfonyl)biphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetate 36.

Sources & evidence

ORD record
ord-d1fbecf0cb4349bfa098347aa35a8c7e
Source dataset
uspto-grants-2015_03
Patent number
US08987318B2

Reaction notes

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