N-bromobutanimide → HCID 89783130, compound

HRID 877448Notes

Reaction equation

[Br:1]N1C(=O)CCC1=O.[CH3:9][S:10]([C:13]1[CH:14]=[C:15]([C:19]2[CH:24]=[CH:23][C:22]([C:25]3[N:29]([CH2:30][C:31]([O:33][CH2:34][CH2:35][N:36]([CH3:38])[CH3:37])=[O:32])[N:28]=[C:27]([C:39]([F:42])([F:41])[F:40])[CH:26]=3)=[CH:21][CH:20]=2)[CH:16]=[CH:17][CH:18]=1)(=[O:12])=[O:11]>>[Br:1][C:26]1[C:27]([C:39]([F:42])([F:41])[F:40])=[N:28][N:29]([CH2:30][C:31]([O:33][CH2:34][CH2:35][N:36]([CH3:38])[CH3:37])=[O:32])[C:25]=1[C:22]1[CH:23]=[CH:24][C:19]([C:15]2[CH:16]=[CH:17][CH:18]=[C:13]([S:10]([CH3:9])(=[O:12])=[O:11])[CH:14]=2)=[CH:20][CH:21]=1

Participants

Reactant 2

HCID 67184N-bromobutanimide

HCID 89782856HCID 89782856, compound

Product 1

HCID 89783130HCID 89783130, compound

Procedure

Following bromination with N-bromosuccinimide, the title compound 40 is prepared starting from 2-(dimethylamino)ethyl 2-(5-(3′-(methylsulfonyl)biphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetate 39.

Sources & evidence

ORD record: ord-bed3f41eefdd439c93ae0dc0b57791f8
Source dataset: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08987318B2

Reaction notes

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