N-bromobutanimide → HCID 89782815, compound

HRID 877450Notes

Reaction equation

HRID 877450 reaction equation
[Br:1]N1C(=O)CCC1=O.[CH3:9][S:10]([C:13]1[CH:14]=[C:15]([C:19]2[CH:24]=[CH:23][C:22]([C:25]3[N:29]([CH2:30][C:31]([O:33][CH2:34][S:35][CH3:36])=[O:32])[N:28]=[C:27]([C:37]([F:40])([F:39])[F:38])[CH:26]=3)=[CH:21][CH:20]=2)[CH:16]=[CH:17][CH:18]=1)(=[O:12])=[O:11]>>[Br:1][C:26]1[C:27]([C:37]([F:40])([F:39])[F:38])=[N:28][N:29]([CH2:30][C:31]([O:33][CH2:34][S:35][CH3:36])=[O:32])[C:25]=1[C:22]1[CH:21]=[CH:20][C:19]([C:15]2[CH:16]=[CH:17][CH:18]=[C:13]([S:10]([CH3:9])(=[O:11])=[O:12])[CH:14]=2)=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 89782949HCID 89782949, compound

Product 1

HCID 89782815HCID 89782815, compound

Procedure

Following bromination with N-bromosuccinimide, the title compound 42 is prepared starting from methylthiomethyl 2-(5-(3′-(methylsulfonyl)biphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetate 41.

Sources & evidence

ORD record
ord-feda47cdd33e43fd945a4bb32052ea57
Source dataset
uspto-grants-2015_03
Patent number
US08987318B2

Reaction notes

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