反应详情

温度

0 °C

Ethyl 2-oxocyclohexanecarboxylate (2 g, 11.7 mmol) was dissolved in water (2 mL), cooled to 0° C. and 5N aqueous .NaOH (5 mL) was added, cooled to room temperature and stirred for 12 h. The reaction mixture was cooled to 0° C., acidified with conc. (pH=2) and used in the next step without any purification.

1. temperaturecooled to room temperature
2. temperatureThe reaction mixture was cooled to 0° C.
3. customused in the next step without any purification