HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Difluorophenylboronic acid → HCID 86670711, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Difluorophenylboronic acid | HCID 2734336 | — |
| Reactant | N-(4-bromo-pyridin-3-yl)-N-methyl-3,5-bis-trifluoromethyl-benzamide | HCID 86670692 | — |
| Product | HCID 86670711 | HCID 86670711 | — |
Reaction Steps
The title compound was prepared in analogy to example 58, from N-(4-bromo-pyridin-3-yl)-N-methyl-3,5-bis-trifluoromethyl-benzamide (example 25, intermediate a) and 2,6-difluorophenyl-boronic acid (CAS RN 162101-25-9) and using preparative HPLC for the chromatographic purification. Off-white solid (16%). MS (ESI): m/z=461.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987307B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-f6536c089cd341c7bd03da3a25c4aa02 |
| Source note | uspto-grants-2015_03 |