HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-fluorobenzeneboronic acid → HCID 86670713, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-fluorobenzeneboronic acid | HCID 17750229 | — |
| Reactant | N-(4-bromo-pyridin-3-yl)-N-methyl-3,5-bis-trifluoromethyl-benzamide | HCID 86670692 | — |
| Product | HCID 86670713 | HCID 86670713 | — |
Reaction Steps
The title compound was prepared in analogy to example 58, from N-(4-bromo-pyridin-3-yl)-N-methyl-3,5-bis-trifluoromethyl-benzamide (example 25, intermediate a) and 2-chloro-4-fluorophenyl-boronic acid (CAS RN 313545-72-1) and using preparative HPLC for the chromatographic purification. Brown sticky solid (33%). MS (ESI): m/z=476.8 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987307B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-41ab9a52e9a74a128637f313a22bc0b1 |
| Source note | uspto-grants-2015_03 |