HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoropyridine-4-boronic acid → (3'-Fluoro-[4,4]bipyridinyl-3-yl)-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoropyridine-4-boronic acid | HCID 2779353 | — |
| Reactant | N-Methyl-N-(2-methyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-yl)-3,5-bis-trifluoromethyl-benzamide | HCID 86670691 | — |
| Product | (3'-Fluoro-[4,4]bipyridinyl-3-yl)-methyl-amine | HCID 70663376 | — |
Reaction Steps
The title compound was prepared in analogy to example 69, intermediate, from (4-bromo-pyridin-3-yl)-methyl-amine (example 25, intermediate b) and 3-fluoropyridine-4-boronic acid (CAS RN 458532-97-3). Brown solid (92%). MS (ESI): m/z=204.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987307B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-68cdb44f69aa4f13aa67e5b719ea6945 |
| Source note | uspto-grants-2015_03 |