HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloropyridine-2-boronic acid → (6-Chloro-[2,4]bipyridinyl-3'-yl)-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloropyridine-2-boronic acid | HCID 22832087 | — |
| Reactant | N-Methyl-N-(2-methyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-yl)-3,5-bis-trifluoromethyl-benzamide | HCID 86670691 | — |
| Product | (6-Chloro-[2,4]bipyridinyl-3'-yl)-methyl-amine | HCID 86670716 | — |
Reaction Steps
The title compound was prepared in analogy to example 68, intermediate, from (4-bromo-pyridin-3-yl)-methyl-amine (example 25, intermediate b) and 6-chloropyridine-2-boronic acid (CAS RN 652148-90-8). Brown sticky solid (90%). MS (ESI): m/z=220.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987307B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-1fd3010b0e064f808f25931aa7af71d4 |
| Source note | uspto-grants-2015_03 |