2-Chlorophenylboronic acid → HCID 86670731, compound

HRID 878106Notes

Reaction equation

HRID 878106 reaction equation
[C:1]([O:5][C:6](=[O:18])[N:7]([CH2:15][CH2:16][F:17])[C:8]1[CH:9]=[N:10][CH:11]=[CH:12][C:13]=1I)([CH3:4])([CH3:3])[CH3:2].[Cl:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1B(O)O>>[C:1]([O:5][C:6](=[O:18])[N:7]([C:8]1[CH:9]=[N:10][CH:11]=[CH:12][C:13]=1[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[Cl:19])[CH2:15][CH2:16][F:17])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 27343222-Chlorophenylboronic acidHCID 86670732HCID 86670732, compound

Product 1

HCID 86670731HCID 86670731, compound

Procedure

The title compound was prepared in analogy to example 72, from (2-fluoro-ethyl)-(4-iodo-pyridin-3-yl)-carbamic acid tert-butyl ester and 2-chlorophenylboronic acid (CAS RN 1679-18-1). Yellow oil (86%). MS (ESI): m/z=351.13 [M+H]+.

Sources & evidence

ORD record
ord-29d6058a6a5b4149bb04c0b7c88be80a
Source dataset
uspto-grants-2015_03
Patent number
US08987307B2

Reaction notes

Loading…