HRID878132

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(C)S(=O)(=O)c1cc(C(=O)O)cc(C(F)(F)F)c1

HCID17964008

未命名化合物

HCID18403336

未命名化合物

PRODUCTS

生成物

结构：Cc1ccccc1-c1ccncc1N(C)C(=O)c1cc(C(F)(F)F)cc(S(=O)(=O)N(C)C)c1

HCID70663485

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to example 90, from N-methyl-4-o-tolylpyridin-3-amine (example 1, intermediate a) and 3-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)benzoic acid (Butt Park Ltd.). The product was purified a second time using preparative HPLC (Phenomenex Gemini® column) and a gradient of acetonitrile:water (containing 0.05% formic acid) (10:90 to 98:2). Light brown foam (20%). MS (ESI): m/z=478.1 [M+H]+.

WORKUP

后处理

customThe product was purified a second time