HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → (4r)-4-[5-(1H-Indol-5-yl)pyridin-2-yloxy]-1-azatricyclo[3.3.1.13,7]decane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-Indolylboronic acid | HCID 2734361 | — |
| Reactant | (4s)-4-(5-Bromopyridin-2-yloxy)-1-azatricyclo[3.3.1.13,7]decane | HCID 24990114 | — |
| Product | (4r)-4-[5-(1H-Indol-5-yl)pyridin-2-yloxy]-1-azatricyclo[3.3.1.13,7]decane | HCID 86621322 | — |
Reaction Steps
Prepared from the product of Example 10C (45 mg, 0.14 mmol) and 5-indolylboronic acid (33 mg, 0.204 mmol; Maybridge) according to Method G: MS (DCI/NH3) m/z=346 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987453B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-7ead1b502b9c44d3a2df3c9fca470ac8 |
| Source note | uspto-grants-2015_03 |