p-Toluenesulfonic acid monohydrate → HCID 86681383, compound

Participants

Reaction Steps

Prepared from the product of Example 36A (77 mg, 0.24 mmol) and p-toluenesulfonic acid monohydrate (93 mg, 0.49 mmol; Aldrich) according to Method H: 1H NMR (300 MHz, methanol-D4) δ ppm 1.98 (d, J=12.5 Hz, 2H), 2.22 (s, 1H), 2.26-2.39 (m, 8H), 2.69 (s, 2H), 3.59 (s, 2H), 3.63-3.78 (m, 4H), 5.57 (t, J=3.2 Hz, 1H), 7.22 (d, J=8.5 Hz, 4H), 7.67-7.74 (m, 4H), 8.12-8.17 (m, 2H), 8.25 (s, 1H), 8.67-8.73 (m, 2H). MS (ESI) m/z=314 (M+H)+. Anal. Calcd. for C17H19N3OS.2C7H8O3S.0.2H2O: C, 56.29; H, 5.39; N, 6.35. Found: C, 56.03; H, 5.29; N, 6.12.

Provenance & Evidence