HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878473Generated: November 1, 2026
Cyclopropylamine → N-cyclopropyl-2-nitroaniline
https://huagongshe.com/reaction/878473
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-cyclopropyl-2-nitroaniline | HCID 10487549 | 32.1% |
Reaction Steps
To a Solution of 1-Fluoro-2-Nitrobenzene (0.50 g, 3.5 Mmol) in Ethanol was Added cyclopropyl amine (0.60 g, 10.5 mmol). The solution was heated to 80° C. overnight and concentrated. The residue was purified by biotage column chromatography to give N-cyclopropyl-2-nitroaniline (0.60 g)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08987468B2 |
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| Source dataset | uspto-grants-2015_03 |
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| ORD ID | ord-faa560f81503410f8fcd6720e18c5701 |
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| Source note | uspto-grants-2015_03 |
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