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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878481Generated: October 30, 2026

Ethyl 3-cyclopropyl-3-oxopropanoate → HCID 178524558, compound

https://huagongshe.com/reaction/878481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-cyclopropyl-3-oxopropanoateHCID 262979—
Reactant2-Hydrazinylpyridine-4-carboxylic acidHCID 26967246—
ProductHCID 178524558HCID 17852455824%

Reaction Steps

The title compound was prepared in 24% yield from 2-hydrazinylpyridine-4-carboxylic acid and ethyl 3-cyclopropyl-3-oxopropanoate according to the procedure for the preparation of Example 1. 1H NMR (400 MHz, CD3OD): δ 0.83-0.88 (2H, m), 1.05-1.09 (2H, m), 1.88-1.91 (1H, m), 4.86 (1H, s), 7.70 (1H, dd, J=5.2, 1.2 Hz), 8.54 (1H, d, J=5.2 Hz), 8.75 (1H, s). [M+H] Calc'd for C12H11N3O3, 246; Found, 246.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987461B2
Source datasetuspto-grants-2015_03
ORD IDord-8a01e586607246349465f37eca2ae956
Source noteuspto-grants-2015_03