HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(2-fluorophenyl)-3-oxopropanoate → HCID 178510210, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(2-fluorophenyl)-3-oxopropanoate | HCID 296342 | — |
| Reactant | 2-Hydrazinylpyridine-4-carbonitrile | HCID 20118714 | — |
| Product | HCID 178510210 | HCID 178510210 | 48% |
Reaction Steps
The title compound was prepared in 48% yield from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and ethyl 3-(2-fluorophenyl)-3-oxopropanoate according to the procedure for the preparation of Example 3, part A. 1H NMR (300 MHz, DMSO-d6): δ 6.15-6.17 (1H, m), 7.13-7.41 (4H, m), 8.07-8.12 (1H, m), 8.34 (1H, s), 8.48-8.50 (1H, m), 11.64 (1H, s). [M+H] Calc'd for C15H9FN4O, 281; Found, 281.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987461B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-6c147075423d4e3cbed097f2443603a0 |
| Source note | uspto-grants-2015_03 |