HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Methoxyacetophenone → (2E)-3-(dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Methoxyacetophenone | HCID 7476 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | (2E)-3-(dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one | HCID 5397461 | 88% |
Reaction Steps
The title compound was prepared in 88% yield from 1-(4-methoxyphenyl)ethanone and DMF-DMA according to the procedure for the preparation of Example 12, part A. 1H NMR (400 MHz, CDCl3): δ 2.88-3.06 (6H, br s), 3.85 (3H, s), 5.71 (1H, d, J=12.0 Hz), 6.91 (2H, d, J=8.8 Hz), 7.84 (1H, d, J=12.0 Hz), 7.91 (2H, d, J=8.8 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987461B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-b00593293a9b43cca1797985bf29dc30 |
| Source note | uspto-grants-2015_03 |