Phenylacetone → HCID 1488370, compound

Participants

Reaction Steps

A solution of 1-phenylpropan-2-one (2.3 g, 20 mmol) and DMF-DMA (2.4 g, 20 mmol) in DMF (10 mL) was stirred at 100° C. overnight. The reaction mixture was cooled, concentrated, and purified by silica gel column (PE/EtOAc=4:1˜2:1) to give the title compound (0.7 g, 18%) as a yellow oil.

Provenance & Evidence